F. Hoffmann-La Roche AG

Switzerland

About Roche

Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare – a strategy that aims to fit the right treatment to each patient in the best way possible.

Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management.

Founded in 1896, Roche continues to search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. The company also aims to improve patient access to medical innovations by working with all relevant stakeholders. More than thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Moreover, for the eleventh consecutive year, Roche has been recognised as one of the most sustainable companies in the Pharmaceuticals Industry by the Dow Jones Sustainability Indices (DJSI).

The Roche Group, headquartered in Basel, Switzerland, is active in over 100 countries and in 2019 employed about 98,000 people worldwide. In 2019, Roche invested CHF 11.7 billion in R&D and posted sales of CHF 61.5 billion. Genentech, in the United States, is a wholly owned member of the Roche Group. Roche is the majority shareholder in Chugai Pharmaceutical, Japan. For more information, please visit www.roche.com.

Roche retains sole responsibility for content ? 2020 F. Hoffmann-La Roche AG. All trademarks used or mentioned in this release are protected by law.

1 December 2018 - 30 November 2019

Region: Global
Subject/journal group: All

The table to the right includes counts of all research outputs for F. Hoffmann-La Roche AG published between 1 December 2018 - 30 November 2019 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

Count Share
139 48.63

Outputs by subject (Share)

Subject Count Share
Chemistry 23 12.08
Life Sciences 119 36.65
Physical Sciences 5 0.93

Highlight of the month

Measles wipes out immune memory

© CHBD/Getty

? CHBD/Getty

Measles infections in children can destroy the immune system’s memory of prior exposure to other pathogens.

The finding — from a team that included scientists at Genentech, a Roche subsidiary — helps explain why youngsters recovering from measles are more susceptible to other infectious diseases. It also underscores the importance of vaccinating against the measles virus.

The researchers analysed blood samples from 77 unvaccinated Dutch children taken before and after a measles outbreak.

They found that the infection erased 11–73% of antibodies against other bacteria and viruses that were present before the children fell ill. Kids who were vaccinated against measles showed no such deficits in their antibody repertoires.

The researchers confirmed that measles induces a kind of immune amnesia by experimentally infecting monkeys with the virus and observing the same loss of pre-existing antibodies.

Supported content

  1. Science 366, 599–606 (2019). doi: 10.1126/science.aay6485

View the article on the Nature Index

See more research highlights from F. Hoffmann-La Roche AG

More research highlights from F. Hoffmann-La Roche AG

1 December 2018 - 30 November 2019

International vs. domestic collaboration by Share

  • 7.1% Domestic
  • 92.9% International

Note: Hover over the graph to view the percentage of collaboration.

Note: Collaboration is determined by the fractional count (Share), which is listed in parentheses.

Affiliated joint institutions and consortia

Return to institution outputs

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